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KMID : 1143420220150422707
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Public Health Weekly Report
2022 Volume.15 No. 42 p.2707 ~ p.2715
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Yersinia pestis: Characteristics and Laboratory Diagnosis
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Pyo Seong-Wook
Kim So-Hyeon
Yi Hwa-Jung
Rhie Gi-Eun
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Abstract
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Yersinia pestis is a facultative anaerobic, Gram-negative coco-bacillus and causative agent of the zoonotic disease plague. Y. pestis is a high-risk pathogen that can be transmitted to humans by the bite of infected fleas or rodents, direct contact with infectious body fluids or tissues, and inhalation of respiratory droplets from a person with pneumonic plague. According to clinical symptoms, plague is divided into bubonic plague, septicaemic plague and pneumonic plague. Especially, pneumonic plague can be a very dangerous disease with a case-fatality ratio of close to 100%. For the laboratory diagnosis of Y. pestis,various diagnostic methods through the culture and isolation of pathogen are being used. Currently, the plague is sporadically occurring in Democratic Republic of the Congo, Madagascar and Peru. There have been no cases in Republic of Korea, but prompt response and diagnosis are required in case of suspected cases caused by foreign imports or bioterrorism. For this purpose, it is important to understand the plague with continuous education and to prepare for laboratory tests.
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KEYWORD
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Yersinia pestis, Plague, Laboratory diagnosis, High-risk pathogen
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